Structured Summary
Abstract
A potent and specific HIV protease inhibitor that appears to have good oral bioavailability.
Chemical Identity
Chemical Information
- Molecular Formula
- C36H47N5O4
- Molecular Weight
- 613.8 g/mol
- CAS Registry No.
- 150378-17-9
- IUPAC Name
- (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide
- InChIKey
- CBVCZFGXHXORBI-PXQQMZJSSA-N
- SMILES
- CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@H](C[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@@H](CC4=CC=CC=C34)O)O)CC5=CN=CC=C5
- MeSH Unique ID
- D019469
- Source
- PubChem CID 5362440
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
13 entry terms
- Crixivan
- Indinavir Sulfate
- Indinavir, Sulfate (1:1)
- L-735 524
- L-735,524
- MK-639
- L 735 524
- L 735,524
- L735 524
- L735,524
- MK 639
- MK639
- Sulfate, Indinavir
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
97; was INDINAVIR (NM) 1994-96
MeSH Record
Previous Indexing
- Pyridines (1994-1996)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Indinavir. Medical Subject Headings (MeSH). 2026. Unique ID D019469. http://id.nlm.nih.gov/mesh/2026/D019469
- Indinavir. In: Wikipedia. https://en.wikipedia.org/wiki/Indinavir
- Indinavir. In: Wikidata. https://www.wikidata.org/wiki/Q425490
- Indinavir. In: PubChem Compound. CID 5362440. https://pubchem.ncbi.nlm.nih.gov/compound/5362440