Chemicals and Drugs

Inflammasomes

Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.

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Synonyms

3 entry terms
  • Inflammasome
  • Pyroptosome
  • Pyroptosomes

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2011

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AMA Style

References

  1. National Library of Medicine. Inflammasomes. Medical Subject Headings (MeSH). 2026. Unique ID D058847. http://id.nlm.nih.gov/mesh/2026/D058847
  2. Inflammasomes. In: Wikipedia. https://en.wikipedia.org/wiki/Inflammasome
  3. Inflammasomes. In: Wikidata. https://www.wikidata.org/wiki/Q412405