Chemicals and Drugs

Inositol Polyphosphate 5-Phosphatases

Phosphoinositide phosphatases that catalyze the removal of the 5' phosphate from INOSITOL 1,4,5-TRISPHOSPHATE or myo-inositol 1,3,4,5-tetrakisphosphate, resulting in inositol 1,4-bisphosphate and phosphate. They have important functions in the metabolism of INOSITOL PHOSPHATES and inositol 1,4,5-trisphosphate signaling pathways such as CALCIUM SIGNALING.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Phosphoinositide phosphatases that catalyze the removal of the 5' phosphate from INOSITOL 1,4,5-TRISPHOSPHATE or myo-inositol 1,3,4,5-tetrakisphosphate, resulting in inositol 1,4-bisphosphate and phosphate. They have important functions in the metabolism of INOSITOL PHOSPHATES and inositol 1,4,5-trisphosphate signaling pathways such as CALCIUM SIGNALING.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

12 entry terms
  • Inositol 5-Phosphatase
  • Inositol Polyphosphate 5-Phosphatase
  • Inositol Triphosphate 5-Phosphatase
  • Inositol-Polyphosphate 5-Phosphatase
  • Inositol 5 Phosphatase
  • Inositol Polyphosphate 5 Phosphatase
  • Inositol Polyphosphate 5 Phosphatases
  • Inositol Triphosphate 5 Phosphatase
  • 1,4,5-Triphosphate-1,2,4,5-Tetrakisphosphate 5-Phosphatase
  • Inositol-1,4,5-Trisphosphate 5'-Phosphatase
  • Inositol-1,4,5-Trisphosphate 5-Phosphatase
  • Ins(1,4,5)P3 5'-Phosphatase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1987)

MeSH Hierarchy

Tree Number

  1. D08.811w.277w.352w.650w.624.500w

AMA Style

References

  1. National Library of Medicine. Inositol Polyphosphate 5-Phosphatases. Medical Subject Headings (MeSH). 2026. Unique ID D000072181. http://id.nlm.nih.gov/mesh/2026/D000072181
  2. Inositol Polyphosphate 5-Phosphatases. In: Wikipedia. https://en.wikipedia.org/wiki/Inositol-polyphosphate_5-phosphatase
  3. Inositol Polyphosphate 5-Phosphatases. In: Wikidata. https://www.wikidata.org/wiki/Q10640340