Chemicals and Drugs

Integrases

Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.

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Synonyms

1 entry terms
  • Integrase

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Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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Indexing Annotation

HIV INTEGRASE is also available

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History Note

2004(1997); use INTEGRASE (NM) 1974-1996

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Previous Indexing

  • Coliphages/enzymology (1974-1980)
  • DNA Helicases (1974-1987)
  • DNA Nucleotidyltransferases (1974-1996)
  • Viral Proteins (1980-1987)

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References

  1. National Library of Medicine. Integrases. Medical Subject Headings (MeSH). 2026. Unique ID D019426. http://id.nlm.nih.gov/mesh/2026/D019426
  2. Integrases. In: Wikidata. https://www.wikidata.org/wiki/Q108456851