Chemicals and Drugs

Integrin-Binding Sialoprotein

A highly glycosylated and sulfated phosphoprotein that is found almost exclusively in mineralized connective tissues. It is an extracellular matrix protein that binds to hydroxyapatite through polyglutamic acid sequences and mediates cell attachment through an RGD sequence.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A highly glycosylated and sulfated phosphoprotein that is found almost exclusively in mineralized connective tissues. It is an extracellular matrix protein that binds to hydroxyapatite through polyglutamic acid sequences and mediates cell attachment through an RGD sequence.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • Bone Sialoprotein
  • Bone Sialoprotein 2
  • Bone Sialoprotein II
  • Integrin Binding Sialoprotein
  • Sialoprotein 2, Bone
  • Sialoprotein, Bone
  • Sialoprotein, Integrin-Binding

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2011

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Integrin-Binding Sialoprotein. Medical Subject Headings (MeSH). 2026. Unique ID D058574. http://id.nlm.nih.gov/mesh/2026/D058574
  2. Integrin-Binding Sialoprotein. In: Wikidata. https://www.wikidata.org/wiki/Q4941582