Structured Summary
Abstract
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
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Classification
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Synonyms
8 entry terms
- IFN-Stimulated Gene Factor 3 Complex
- ISGF3 Factor
- ISGF3 Transcription Factor
- Transcription Factor ISGF3
- IFN Stimulated Gene Factor 3 Complex
- ISGF3, Transcription Factor
- Interferon Stimulated Gene Factor 3
- Transcription Factor, ISGF3
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1990)
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AMA Style
References
- National Library of Medicine. Interferon-Stimulated Gene Factor 3. Medical Subject Headings (MeSH). 2026. Unique ID D050832. http://id.nlm.nih.gov/mesh/2026/D050832
- Interferon-Stimulated Gene Factor 3. In: Wikidata. https://www.wikidata.org/wiki/Q21173487