Chemicals and Drugs

Interferon Regulatory Factors

A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.

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Classification

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MeSH Record

Synonyms

5 entry terms
  • IRF Transcription Factors
  • Interferon Regulatory Factor
  • Factor, Interferon Regulatory
  • Regulatory Factor, Interferon
  • Transcription Factors, IRF

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006

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AMA Style

References

  1. National Library of Medicine. Interferon Regulatory Factors. Medical Subject Headings (MeSH). 2026. Unique ID D050835. http://id.nlm.nih.gov/mesh/2026/D050835
  2. Interferon Regulatory Factors. In: Wikipedia. https://en.wikipedia.org/wiki/Interferon_regulatory_factors
  3. Interferon Regulatory Factors. In: Wikidata. https://www.wikidata.org/wiki/Q6046461