Chemicals and Drugs

Interleukin-11

A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

6 entry terms
  • Adipogenesis Inhibitory Factor
  • IL-11
  • IL11
  • Factor, Adipogenesis Inhibitory
  • Inhibitory Factor, Adipogenesis
  • Interleukin 11

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

93; was INTERLEUKIN 11 (NM) 1990-92

MeSH Record

Previous Indexing

  • Interleukins (1990-1992)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Interleukin-11. Medical Subject Headings (MeSH). 2026. Unique ID D017370. http://id.nlm.nih.gov/mesh/2026/D017370
  2. Interleukin-11. In: Wikidata. https://www.wikidata.org/wiki/Q24784118