Chemicals and Drugs

Interleukin-1 Receptor-Associated Kinases

A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.

MeSH Record

Classification

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MeSH Record

Synonyms

33 entry terms
  • IL-1 Receptor-Associated Kinase
  • IRAK Kinases
  • Interleukin-1 Receptor-Associated Kinase
  • IL 1 Receptor Associated Kinase
  • Interleukin 1 Receptor Associated Kinase
  • Interleukin 1 Receptor Associated Kinases
  • Kinase, IL-1 Receptor-Associated
  • Kinase, Interleukin-1 Receptor-Associated
  • Kinases, IRAK
  • Kinases, Interleukin-1 Receptor-Associated
  • Receptor-Associated Kinase, IL-1
  • Receptor-Associated Kinase, Interleukin-1
  • Receptor-Associated Kinases, Interleukin-1
  • IRAK-1 Kinase
  • IRAK-2 Kinase
  • IRAK-3 Kinase
  • IRAK-4 Kinase
  • Interleukin-1 Receptor-Associated Kinase 1
  • Interleukin-1 Receptor-Associated Kinase 2
  • Interleukin-1 Receptor-Associated Kinase 3
  • Interleukin-1 Receptor-Associated Kinase 4
  • IRAK 1 Kinase
  • IRAK 2 Kinase
  • IRAK 3 Kinase
  • IRAK 4 Kinase
  • Interleukin 1 Receptor Associated Kinase 1
  • Interleukin 1 Receptor Associated Kinase 2
  • Interleukin 1 Receptor Associated Kinase 3
  • Interleukin 1 Receptor Associated Kinase 4
  • Kinase, IRAK-1
  • Kinase, IRAK-2
  • Kinase, IRAK-3
  • Kinase, IRAK-4

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1996)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Interleukin-1 Receptor-Associated Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D053592. http://id.nlm.nih.gov/mesh/2026/D053592
  2. Interleukin-1 Receptor-Associated Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/Interleukin-1_receptor_associated_kinase
  3. Interleukin-1 Receptor-Associated Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q6046925