Chemicals and Drugs

Interleukin 1 Receptor Antagonist Protein

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • IL-1 Inhibitor, Urine
  • IL-1Ra
  • IL1 Febrile Inhibitor
  • Interleukin 1 Inhibitor, Urine
  • Urine-Derived IL1 Inhibitor
  • Febrile Inhibitor, IL1
  • IL 1 Inhibitor, Urine
  • IL1 Inhibitor, Urine-Derived
  • Urine Derived IL1 Inhibitor
  • Urine IL-1 Inhibitor
  • Anakinra
  • Antril
  • Kineret

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Interleukin 1 Receptor Antagonist Protein. Medical Subject Headings (MeSH). 2026. Unique ID D053590. http://id.nlm.nih.gov/mesh/2026/D053590
  2. Interleukin 1 Receptor Antagonist Protein. In: Wikidata. https://www.wikidata.org/wiki/Q4066948