Chemicals and Drugs

Iodothyronine Deiodinase Type II

An enzyme responsible for T4 (3,5,3',5'-tetraiodothyronine) to T3 (3,5,3'-TRIIODOTHYRONINE) conversion. May contribute to increasing T3 THYROID HORMONE production in patients with GRAVES DISEASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme responsible for T4 (3,5,3',5'-tetraiodothyronine) to T3 (3,5,3'-TRIIODOTHYRONINE) conversion. May contribute to increasing T3 THYROID HORMONE production in patients with GRAVES DISEASE.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

16 entry terms
  • DIO2 Enzyme
  • Selenodeiodinase Type 2
  • TXDI2 Enzyme
  • Type 2 Deiodinase (D2)
  • Type 2 Selenodeiodinase
  • Type II 5'-Deiodinase
  • Type II Iodothyronine Deiodinase
  • 2 Selenodeiodinase, Type
  • 2, Selenodeiodinase Type
  • 5'-Deiodinase, Type II
  • Enzyme, DIO2
  • Enzyme, TXDI2
  • II 5'-Deiodinase, Type
  • Selenodeiodinase, Type 2
  • Type 2, Selenodeiodinase
  • Type II 5' Deiodinase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2024 (1996)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Iodothyronine Deiodinase Type II. Medical Subject Headings (MeSH). 2026. Unique ID D000097564. http://id.nlm.nih.gov/mesh/2026/D000097564
  2. Iodothyronine Deiodinase Type II. In: Wikidata. https://www.wikidata.org/wiki/Q21120665