Chemicals and Drugs

Iofetamine

An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

Chemical Identity

Chemical Information

Molecular Formula
C12H18IN
Molecular Weight
299.18 g/mol
CAS Registry No.
75917-92-9
IUPAC Name
1-(4-iodophenyl)-N-propan-2-ylpropan-2-amine
InChIKey
ISEHJSHTIVKELA-DCWJVSPSSA-N
SMILES
CC(C)NC(C)CC1=CC=C(C=C1)[123I]
MeSH Unique ID
D020367
Source
PubChem CID 156375

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • N-Isopropyl-p-iodoamphetamine
  • N Isopropyl p iodoamphetamine
  • Iodine-123-IMP
  • Iofetamine Hydrochloride, I-123
  • Iofetamine I-123
  • N-Isopropyl-p-(Iodine-123)-Iodoamphetamine
  • N-Isopropyl-p-iodoamphetamine (I123) Hydrochloride
  • Hydrochloride, I-123 Iofetamine
  • I-123 Iofetamine Hydrochloride
  • I-123, Iofetamine
  • Iodine 123 IMP
  • Iofetamine Hydrochloride, I 123
  • Iofetamine I 123

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

99; use IOFETAMINE (NM) 1980-98

MeSH Record

Previous Indexing

  • Amphetamines (1980-1998)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Iofetamine. Medical Subject Headings (MeSH). 2026. Unique ID D020367. http://id.nlm.nih.gov/mesh/2026/D020367
  2. Iofetamine. In: Wikipedia. https://en.wikipedia.org/wiki/Iofetamine_(123I)
  3. Iofetamine. In: Wikidata. https://www.wikidata.org/wiki/Q15409426
  4. Iofetamine. In: PubChem Compound. CID 156375. https://pubchem.ncbi.nlm.nih.gov/compound/156375