Chemicals and Drugs

Isoamylase

An enzyme that hydrolyzes 1,6-alpha-glucosidic branch linkages in glycogen, amylopectin, and their beta-limit dextrins. It is distinguished from pullulanase (EC 3.2.1.41) by its inability to attack pullulan and by the feeble action of alpha-limit dextrins. It is distinguished from amylopectin 6-glucanohydrolase (EC 3.2.1.69) by its action on glycogen. With EC 3.2.1.69, it produces the activity called debranching enzyme. EC 3.2.1.68.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that hydrolyzes 1,6-alpha-glucosidic branch linkages in glycogen, amylopectin, and their beta-limit dextrins. It is distinguished from pullulanase (EC 3.2.1.41) by its inability to attack pullulan and by the feeble action of alpha-limit dextrins. It is distinguished from amylopectin 6-glucanohydrolase (EC 3.2.1.69) by its action on glycogen. With EC 3.2.1.69, it produces the activity called debranching enzyme. EC 3.2.1.68.

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Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with amylase isoenzymes (index under AMYLASES (IM) + ISOENZYMES (IM) )

MeSH Record

History Note

91(75); was see under GLYCOSIDE HYDROLASES 1975-90

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Previous Indexing

  • Glycoside Hydrolases (1974)
  • Polysaccharides (1974)

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References

  1. National Library of Medicine. Isoamylase. Medical Subject Headings (MeSH). 2026. Unique ID D007517. http://id.nlm.nih.gov/mesh/2026/D007517
  2. Isoamylase. In: Wikipedia. https://en.wikipedia.org/wiki/Isoamylase
  3. Isoamylase. In: Wikidata. https://www.wikidata.org/wiki/Q10893043