Structured Summary
Abstract
A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the naturally occurring compounds.
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MeSH Record
Synonyms
1 entry terms
- Isoprostane
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2002
MeSH Record
Previous Indexing
- Dinoprost (1992-2001)
- Lipid Peroxides (1992-2001)
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References
- National Library of Medicine. Isoprostanes. Medical Subject Headings (MeSH). 2026. Unique ID D028421. http://id.nlm.nih.gov/mesh/2026/D028421
- Isoprostanes. In: Wikipedia. https://en.wikipedia.org/wiki/Isoprostane
- Isoprostanes. In: Wikidata. https://www.wikidata.org/wiki/Q4198767