Chemicals and Drugs

Kanamycin Kinase

A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.

MeSH Record

Classification

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MeSH Record

Synonyms

26 entry terms
  • Amikacin 3'-Phosphotransferase
  • Aminocyclitol Phosphotransferase
  • Aminoglycoside 3'-Phosphotransferase Type VIII
  • Aminoglycoside Phosphotransferase
  • Kanamycin-Neomycin Phosphate Transferase
  • Neomycin Phosphotransferase
  • 3'-Phosphotransferase, Amikacin
  • Amikacin 3' Phosphotransferase
  • Aminoglycoside 3' Phosphotransferase Type VIII
  • Kanamycin Neomycin Phosphate Transferase
  • Kinase, Kanamycin
  • Phosphate Transferase, Kanamycin-Neomycin
  • Phosphotransferase, Aminocyclitol
  • Phosphotransferase, Aminoglycoside
  • Phosphotransferase, Neomycin
  • Transferase, Kanamycin-Neomycin Phosphate
  • APH(3')-IIIa
  • APH(3')-IIb
  • APHVII
  • APT-3'-I and II
  • Aminoglycoside 3'-Phosphotransferases (I and II)
  • Aminoglycoside Phosphotransferase Type III
  • Neomycin Phosphotransferase II
  • aphVII Gene Product
  • APT 3' I and II
  • Phosphotransferase II, Neomycin

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98; use KANAMYCIN KINASE (NM) 1980-97

MeSH Record

Previous Indexing

  • Kanamycin (1976-1980)
  • Phosphotransferases (1976-1993)
  • Phosphotransferases (Alcohol Group Acceptor) (1994-1997)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Kanamycin Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D019868. http://id.nlm.nih.gov/mesh/2026/D019868
  2. Kanamycin Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Kanamycin_kinase
  3. Kanamycin Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q6360598