Chemicals and Drugs

Keratin-12

A type I keratin that is found associated with the KERATIN-3 in the CORNEA and is regarded as a marker for corneal-type epithelial differentiation. Mutations in the gene for keratin-12 have been associated with MEESMANN CORNEAL EPITHELIAL DYSTROPHY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A type I keratin that is found associated with the KERATIN-3 in the CORNEA and is regarded as a marker for corneal-type epithelial differentiation. Mutations in the gene for keratin-12 have been associated with MEESMANN CORNEAL EPITHELIAL DYSTROPHY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Cytokeratin-12
  • Keratin 12
  • Cytokeratin 12

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(2003)

MeSH Record

Previous Indexing

  • Keratin (1992-2006)

MeSH Hierarchy

Tree Numbers

  1. D05.750w.078w.593.450w.300w.200
  2. D12.776w.220.475.450w.300w.200
  3. D12.776w.860w.607w.300w.200

AMA Style

References

  1. National Library of Medicine. Keratin-12. Medical Subject Headings (MeSH). 2026. Unique ID D053551. http://id.nlm.nih.gov/mesh/2026/D053551
  2. Keratin-12. In: Wikidata. https://www.wikidata.org/wiki/Q4219506