Chemicals and Drugs

Ketocholesterols

Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits cholesterol uptake in the coronary arteries and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits cholesterol uptake in the coronary arteries and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

1 entry terms
  • Oxocholesterols

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(80); was see under CHOLESTEROL 1980-90

MeSH Record

Previous Indexing

  • Cholesterol (1966-1974) /analogs & derivatives (1975-1979)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.247.222w.265.450
  2. D04w.210.500w.247.222w.284w.800w.750
  3. D04w.210.500w.247.808w.197w.800w.750
  4. D10w.570w.938w.208w.825w.750

AMA Style

References

  1. National Library of Medicine. Ketocholesterols. Medical Subject Headings (MeSH). 2026. Unique ID D007653. http://id.nlm.nih.gov/mesh/2026/D007653
  2. Ketocholesterols. In: Wikidata. https://www.wikidata.org/wiki/Q76626749