Structured Summary
Abstract
Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
Chemical Identity
Chemical Information
- Molecular Formula
- C26H28Cl2N4O4
- Molecular Weight
- 531.4 g/mol
- IUPAC Name
- 1-[4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
- InChIKey
- XMAYWYJOQHXEEK-UHFFFAOYSA-N
- SMILES
- CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
- MeSH Unique ID
- D007654
- Source
- PubChem CID 3823
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
5 entry terms
- Nizoral
- R-41400
- R41,400
- R41400
- R 41400
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
84
MeSH Record
Previous Indexing
- Imidazoles (1966-1983)
- Piperazines (1966-1983)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QV 252
AMA Style
References
- National Library of Medicine. Ketoconazole. Medical Subject Headings (MeSH). 2026. Unique ID D007654. http://id.nlm.nih.gov/mesh/2026/D007654
- Ketoconazole. In: Wikipedia. https://en.wikipedia.org/wiki/Ketoconazole
- Ketoconazole. In: Wikidata. https://www.wikidata.org/wiki/Q407883
- Ketoconazole. In: PubChem Compound. CID 3823. https://pubchem.ncbi.nlm.nih.gov/compound/3823