Chemicals and Drugs

Kinetoplast DNA

DNA of kinetoplasts which are specialized MITOCHONDRIA of trypanosomes and related parasitic protozoa within the order KINETOPLASTIDA. Kinetoplast DNA consists of a complex network of numerous catenated rings of two classes; the first being a large number of small DNA duplex rings, called minicircles, approximately 2000 base pairs in length, and the second being several dozen much larger rings, called maxicircles, approximately 37 kb in length.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA of kinetoplasts which are specialized MITOCHONDRIA of trypanosomes and related parasitic protozoa within the order KINETOPLASTIDA. Kinetoplast DNA consists of a complex network of numerous catenated rings of two classes; the first being a large number of small DNA duplex rings, called minicircles, approximately 2000 base pairs in length, and the second being several dozen much larger rings, called maxicircles, approximately 37 kb in length.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

12 entry terms
  • DNA, Kinetoplast
  • kDNA
  • Kinetoplast DNA Maxicircles
  • Kinetoplast DNA Minicircles
  • kDNA Maxicircles
  • kDNA Minicircles
  • DNA Maxicircles, Kinetoplast
  • DNA Minicircles, Kinetoplast
  • Maxicircles, Kinetoplast DNA
  • Maxicircles, kDNA
  • Minicircles, Kinetoplast DNA
  • Minicircles, kDNA

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

protozoan DNA; from Kinetoplastida, an order of flagellate protozoa; coord IM with specific protozoon (IM); /drug eff /ultrastruct permitted

MeSH Record

History Note

94; was KINETOPLAST DNA (NM) 1987-93; KINETOPLAST DNA MAXICIRCLES was NM 1987-93; KINETOPLAST DNA MINICIRCLES was NM 1980-93

MeSH Record

Previous Indexing

  • DNA (1969-1973)
  • DNA, Circular (1973-1993)
  • DNA, Protozoan (1991-1993)

MeSH Hierarchy

Tree Numbers

  1. D13.444w.308w.283w.225w.200w
  2. D13.444w.308w.442.200w

AMA Style

References

  1. National Library of Medicine. Kinetoplast DNA. Medical Subject Headings (MeSH). 2026. Unique ID D018105. http://id.nlm.nih.gov/mesh/2026/D018105
  2. Kinetoplast DNA. In: Wikipedia. https://en.wikipedia.org/wiki/Kinetoplast
  3. Kinetoplast DNA. In: Wikidata. https://www.wikidata.org/wiki/Q511594