Chemicals and Drugs

Kruppel-Like Factor 6

A Kruppel-like transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS and binds to GC RICH SEQUENCE (GC box) in upstream gene promoters. It functions as a transcriptional activator, tumor suppressor, and may regulate growth and development of B-cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A Kruppel-like transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS and binds to GC RICH SEQUENCE (GC box) in upstream gene promoters. It functions as a transcriptional activator, tumor suppressor, and may regulate growth and development of B-cells.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • COPEB Protein
  • CPBP Protein
  • Core Promoter Element Binding Protein
  • Kruppel Like Factor 6

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Kruppel-Like Transcription Factors (2006-2017)
  • Proto-Oncogene Proteins (1997-2017)
  • Trans-Activators (1997-2017)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.522w.563
  2. D12.776w.260w.755.050
  3. D12.776w.624.664.700.120
  4. D12.776w.930w.375w.563

AMA Style

References

  1. National Library of Medicine. Kruppel-Like Factor 6. Medical Subject Headings (MeSH). 2026. Unique ID D000075723. http://id.nlm.nih.gov/mesh/2026/D000075723
  2. Kruppel-Like Factor 6. In: Wikidata. https://www.wikidata.org/wiki/Q21118608