Structured Summary
Abstract
An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
20 entry terms
- G22P1 Antigen
- Ku Antigen
- Ku Heterodimer
- Ku Protein
- Antigen, G22P1
- Antigen, Ku
- Autoantigen, Ku
- Heterodimer, Ku
- Ku Autoantigen, 70 kDa
- Ku Autoantigen, 80 kDa
- Ku70 Antigen
- Ku80 Antigen
- X-ray Repair Cross-Complementing Protein 5
- X-ray Repair Cross-Complementing Protein 6
- XRCC5 Protein
- XRCC6 Protein
- Antigen, Ku70
- Antigen, Ku80
- X ray Repair Cross Complementing Protein 5
- X ray Repair Cross Complementing Protein 6
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1986)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Ku Autoantigen. Medical Subject Headings (MeSH). 2026. Unique ID D000072200. http://id.nlm.nih.gov/mesh/2026/D000072200
- Ku Autoantigen. In: Wikipedia. https://en.wikipedia.org/wiki/Ku_(protein)
- Ku Autoantigen. In: Wikidata. https://www.wikidata.org/wiki/Q2088960