Diseases

Landau-Kleffner Syndrome

A syndrome characterized by the onset of isolated language dysfunction in otherwise normal children (age of onset 4-7 years) and epileptiform discharges on ELECTROENCEPHALOGRAPHY. Seizures, including atypical absence (EPILEPSY, ABSENCE), complex partial (EPILEPSY, COMPLEX PARTIAL), and other types may occur. The electroencephalographic abnormalities and seizures tend to resolve by puberty. The language disorder may also resolve although some individuals are left with severe language dysfunction, including APHASIA and auditory AGNOSIA. (From Menkes, Textbook of Child Neurology, 5th ed, pp749-50; J Child Neurol 1997 Nov;12(8):489-495).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A syndrome characterized by the onset of isolated language dysfunction in otherwise normal children (age of onset 4-7 years) and epileptiform discharges on ELECTROENCEPHALOGRAPHY. Seizures, including atypical absence (EPILEPSY, ABSENCE), complex partial (EPILEPSY, COMPLEX PARTIAL), and other types may occur. The electroencephalographic abnormalities and seizures tend to resolve by puberty. The language disorder may also resolve although some individuals are left with severe language dysfunction, including APHASIA and auditory AGNOSIA. (From Menkes, Textbook of Child Neurology, 5th ed, pp749-50; J Child Neurol 1997 Nov;12(8):489-495).

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Broader headings

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MeSH Record

See Also

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Synonyms

17 entry terms
  • Acquired Aphasia with Convulsive Disorder
  • Acquired Childhoood Aphasia with Convulsive Disorder
  • Acquired Epileptiform Aphasia
  • Aphasia, Acquired Epileptic
  • Aphasia, Acquired, With Convulsive Disorder
  • Aphasia, Epileptic, Acquired
  • Landau-Kleffner Acquired Epileptiform Aphasia
  • Acquired Epileptic Aphasia
  • Acquired Epileptic Aphasias
  • Acquired Epileptiform Aphasias
  • Epileptic Aphasia, Acquired
  • Epileptic Aphasias, Acquired
  • Epileptiform Aphasia, Acquired
  • Epileptiform Aphasias, Acquired
  • Landau Kleffner Acquired Epileptiform Aphasia
  • Landau Kleffner Syndrome
  • Syndrome, Landau-Kleffner

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1996

MeSH Record

Previous Indexing

  • Aphasia (1982-1995)
  • Epilepsy (1982-1995)

MeSH Hierarchy

Tree Number

  1. C10w.228w.140w.490w.493w.500w

MeSH Record

NLM Classification

WL 340.5

AMA Style

References

  1. National Library of Medicine. Landau-Kleffner Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D018887. http://id.nlm.nih.gov/mesh/2026/D018887
  2. Landau-Kleffner Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Landau%E2%80%93Kleffner_syndrome
  3. Landau-Kleffner Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q1636310