Diseases

Langerhans-Cell Histiocytosis

A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

66 entry terms
  • Histiocytosis X
  • Histiocytosis, Generalized
  • Histiocytosis, Langerhans-Cell
  • Histiocytosis-X
  • Langerhans Cell Granulomatosis
  • Langerhans Cell Histiocytosis
  • Langerhans-Cell Granulomatosis
  • Non-Lipid Reticuloendotheliosis
  • Schueller-Christian Disease
  • Systemic Aleukemic Reticuloendotheliosis
  • Type 2 Histiocytosis
  • Aleukemic Reticuloendothelioses, Systemic
  • Aleukemic Reticuloendotheliosis, Systemic
  • Cell Granulomatoses, Langerhans
  • Cell Granulomatosis, Langerhans
  • Cell Histiocytoses, Langerhans
  • Cell Histiocytosis, Langerhans
  • Disease, Schueller-Christian
  • Generalized Histiocytoses
  • Generalized Histiocytosis
  • Granulomatoses, Langerhans Cell
  • Granulomatosis, Langerhans Cell
  • Granulomatosis, Langerhans-Cell
  • Histiocytoses, Generalized
  • Histiocytoses, Langerhans Cell
  • Histiocytoses, Type 2
  • Histiocytosis, Langerhans Cell
  • Histiocytosis, Type 2
  • Langerhans Cell Granulomatoses
  • Langerhans Cell Histiocytoses
  • Non Lipid Reticuloendotheliosis
  • Non-Lipid Reticuloendothelioses
  • Reticuloendothelioses, Non-Lipid
  • Reticuloendothelioses, Systemic Aleukemic
  • Reticuloendotheliosis, Non-Lipid
  • Reticuloendotheliosis, Systemic Aleukemic
  • Schueller Christian Disease
  • Systemic Aleukemic Reticuloendothelioses
  • Type 2 Histiocytoses
  • Hand-Schueller-Christian Disease
  • Hand-Schueller-Christian Syndrome
  • Hand-Schüller-Christian Disease
  • Hand-Schüller-Christian Syndrome
  • Hashimoto-Pritzger Disease
  • Hashimoto-Pritzker Disease
  • Hashimoto-Pritzker Histiocytosis
  • Hashimoto-Pritzker Syndrome
  • Langerhans Cell Granulomatosis, Pulmonary
  • Letterer-Siwe Disease
  • Pulmonary Histiocytosis X
  • Pulmonary Langerhans Cell Granulomatosis
  • Disease, Hand-Schueller-Christian
  • Disease, Hand-Schüller-Christian
  • Disease, Hashimoto-Pritzger
  • Disease, Letterer-Siwe
  • Diseases, Hashimoto-Pritzger
  • Hand Schueller Christian Disease
  • Hand Schueller Christian Syndrome
  • Hand Schüller Christian Disease
  • Hand Schüller Christian Syndrome
  • Hashimoto Pritzger Disease
  • Hashimoto-Pritzger Diseases
  • Histiocytosis X, Pulmonary
  • Letterer Siwe Disease
  • Syndrome, Hand-Schueller-Christian
  • Syndrome, Hand-Schüller-Christian

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

90(75); was see under RETICULOENDOTHELIOSIS 1966-75; was HISTIOCYTOSIS X 1975-89

MeSH Record

Previous Indexing

  • Reticuloendotheliosis (1966-1974)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WH 720

AMA Style

References

  1. National Library of Medicine. Langerhans-Cell Histiocytosis. Medical Subject Headings (MeSH). 2026. Unique ID D006646. http://id.nlm.nih.gov/mesh/2026/D006646
  2. Langerhans-Cell Histiocytosis. In: Wikipedia. https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis
  3. Langerhans-Cell Histiocytosis. In: Wikidata. https://www.wikidata.org/wiki/Q374036