Chemicals and Drugs

Lansoprazole

A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Chemical Identity

Chemical Information

Molecular Formula
C16H14F3N3O2S
Molecular Weight
369.4 g/mol
CAS Registry No.
103577-45-3
IUPAC Name
2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylsulfinyl]-1H-benzimidazole
InChIKey
MJIHNNLFOKEZEW-UHFFFAOYSA-N
SMILES
CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
MeSH Unique ID
D064747
Source
PubChem CID 3883

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

23 entry terms
  • 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole
  • Lansoprazol
  • Lansoprazoles
  • AG 1749
  • AG-1749
  • Agopton
  • Bamalite
  • Lansol
  • Lansoprazole Sodium
  • Lanzor
  • Monolitum
  • Ogast
  • Ogastro
  • Opiren
  • Prevacid
  • Prezal
  • Pro Ulco
  • Promeco
  • Takepron
  • Ulpax
  • Zoton
  • AG1749
  • Sodium, Lansoprazole

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2014

MeSH Hierarchy

Tree Numbers

  1. D02w.886w.640w.074.249w
  2. D03w.383.725w.024.249w
  3. D03w.633.100.103.034.249w

AMA Style

References

  1. National Library of Medicine. Lansoprazole. Medical Subject Headings (MeSH). 2026. Unique ID D064747. http://id.nlm.nih.gov/mesh/2026/D064747
  2. Lansoprazole. In: Wikipedia. https://en.wikipedia.org/wiki/Lansoprazole
  3. Lansoprazole. In: Wikidata. https://www.wikidata.org/wiki/Q254296
  4. Lansoprazole. In: PubChem Compound. CID 3883. https://pubchem.ncbi.nlm.nih.gov/compound/3883