Chemicals and Drugs

Leptin

A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

6 entry terms
  • Ob Gene Product
  • Ob Protein
  • Obese Gene Product
  • Obese Protein
  • Gene Product, Ob
  • Gene Product, Obese

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2000; use LEPTIN (NM) 1995-1999

MeSH Record

Previous Indexing

  • Proteins (1995-1999)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.042w.500
  2. D12.644w.276.024w.500
  3. D12.644w.548w.011w.500
  4. D12.776w.467.024w.500
  5. D23.529.024w.500

AMA Style

References

  1. National Library of Medicine. Leptin. Medical Subject Headings (MeSH). 2026. Unique ID D020738. http://id.nlm.nih.gov/mesh/2026/D020738
  2. Leptin. In: Wikidata. https://www.wikidata.org/wiki/Q24787174