Phenomena and Processes

Lethal Genes

Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES, ESSENTIAL) required for viability, or genes which cause a block of function of an essential gene at a time when the essential gene function is required for viability.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES, ESSENTIAL) required for viability, or genes which cause a block of function of an essential gene at a time when the essential gene function is required for viability.

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Classification

Broader headings

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See Also

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Synonyms

7 entry terms
  • Genes, Lethal
  • Gene, Lethal
  • Lethal Gene
  • Alleles, Lethal
  • Allele, Lethal
  • Lethal Allele
  • Lethal Alleles

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

68

MeSH Record

Previous Indexing

  • Genes (1966-1967)

MeSH Hierarchy

Tree Number

  1. G05.360w.340w.024.340w.350w

AMA Style

References

  1. National Library of Medicine. Lethal Genes. Medical Subject Headings (MeSH). 2026. Unique ID D005804. http://id.nlm.nih.gov/mesh/2026/D005804
  2. Lethal Genes. In: Wikipedia. https://en.wikipedia.org/wiki/Lethal_allele
  3. Lethal Genes. In: Wikidata. https://www.wikidata.org/wiki/Q927843