Chemicals and Drugs

Leukemia Inhibitory Factor

An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

11 entry terms
  • Cholinergic Differentiation Factor
  • D Factor (Leukemia Inhibitory Factor)
  • Differentiation-Stimulating Factor
  • Myeloid Differentiation-Stimulating Factor
  • Differentiation Factor, Cholinergic
  • Differentiation Stimulating Factor
  • Differentiation-Stimulating Factor, Myeloid
  • Inhibitory Factor, Leukemia
  • Myeloid Differentiation Stimulating Factor
  • AM424
  • Emfilermin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1980)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Leukemia Inhibitory Factor. Medical Subject Headings (MeSH). 2026. Unique ID D053605. http://id.nlm.nih.gov/mesh/2026/D053605
  2. Leukemia Inhibitory Factor. In: Wikidata. https://www.wikidata.org/wiki/Q24723759