Chemicals and Drugs

Lidocaine

A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.

Chemical Identity

Chemical Information

Molecular Formula
C14H22N2O
Molecular Weight
234.34 g/mol
CAS Registry No.
137-58-6
IUPAC Name
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
InChIKey
NNJVILVZKWQKPM-UHFFFAOYSA-N
SMILES
CCN(CC)CC(=O)NC1=C(C=CC=C1C)C
MeSH Unique ID
D008012
Source
PubChem CID 3676

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

17 entry terms
  • 2-(Diethylamino)-N-(2,6-Dimethylphenyl)Acetamide
  • 2-2EtN-2MePhAcN
  • Lignocaine
  • Dalcaine
  • Lidocaine Carbonate
  • Lidocaine Carbonate (2:1)
  • Lidocaine Hydrocarbonate
  • Lidocaine Hydrochloride
  • Lidocaine Monoacetate
  • Lidocaine Monohydrochloride
  • Lidocaine Monohydrochloride, Monohydrate
  • Lidocaine Sulfate (1:1)
  • Octocaine
  • Xylesthesin
  • Xylocaine
  • Xylocitin
  • Xyloneural

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.199w.092.500w
  2. D02w.092w.146.113w.092.500w

MeSH Record

NLM Classification

QV 110

AMA Style

References

  1. National Library of Medicine. Lidocaine. Medical Subject Headings (MeSH). 2026. Unique ID D008012. http://id.nlm.nih.gov/mesh/2026/D008012
  2. Lidocaine. In: Wikipedia. https://en.wikipedia.org/wiki/Lidocaine
  3. Lidocaine. In: Wikidata. https://www.wikidata.org/wiki/Q216935
  4. Lidocaine. In: PubChem Compound. CID 3676. https://pubchem.ncbi.nlm.nih.gov/compound/3676