Diseases

Limb-Girdle Muscular Dystrophies

A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

9 entry terms
  • Limb-Girdle Muscular Dystrophy
  • Limb-Girdle Syndrome
  • Muscular Dystrophies, Limb-Girdle
  • Muscular Dystrophy, Limb-Girdle
  • Myopathic Limb-Girdle Syndrome
  • Limb Girdle Muscular Dystrophies
  • Limb Girdle Muscular Dystrophy
  • Muscular Dystrophies, Limb Girdle
  • Muscular Dystrophy, Limb Girdle

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, virology.

MeSH Record

History Note

2005; use MUSCULAR DYSTROPHIES 2000-2004

MeSH Record

Previous Indexing

  • Muscular Dystrophies (1966-2004)

MeSH Hierarchy

Tree Numbers

  1. C05w.651w.534.500w.280w
  2. C10w.668w.491w.175.500w.149w
  3. C16w.320w.577w.280w

AMA Style

References

  1. National Library of Medicine. Limb-Girdle Muscular Dystrophies. Medical Subject Headings (MeSH). 2026. Unique ID D049288. http://id.nlm.nih.gov/mesh/2026/D049288
  2. Limb-Girdle Muscular Dystrophies. In: Wikipedia. https://en.wikipedia.org/wiki/Limb%E2%80%93girdle_muscular_dystrophy
  3. Limb-Girdle Muscular Dystrophies. In: Wikidata. https://www.wikidata.org/wiki/Q1531322