Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Limulus Test

Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.

MeSH Record

Classification

Broader headings

Related Concepts

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See Also

MeSH Record

Synonyms

3 entry terms
  • Limulus Tests
  • Test, Limulus
  • Tests, Limulus

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

Indexing Annotation

for detection of bact endotoxins using horseshoe crab blood

MeSH Record

History Note

78

MeSH Record

Previous Indexing

  • Endotoxins (1966-1977)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.124.470
  2. E01w.370.225.875.150.570
  3. E05.091w.570
  4. E05.200.124.470
  5. E05.200.875.150.570

AMA Style

References

  1. National Library of Medicine. Limulus Test. Medical Subject Headings (MeSH). 2026. Unique ID D008033. http://id.nlm.nih.gov/mesh/2026/D008033
  2. Limulus Test. In: Wikidata. https://www.wikidata.org/wiki/Q131244058