Chemicals and Drugs

Linoleic Acid

A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)

Chemical Identity

Chemical Information

Molecular Formula
C18H32O2
Molecular Weight
280.4 g/mol
CAS Registry No.
60-33-3
IUPAC Name
(9Z,12Z)-octadeca-9,12-dienoic acid
InChIKey
OYHQOLUKZRVURQ-HZJYTTRNSA-N
SMILES
CCCCC/C=C\C/C=C\CCCCCCCC(=O)O
MeSH Unique ID
D019787
Source
PubChem CID 5280450

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

20 entry terms
  • 9,12-Octadecadienoic Acid
  • 9,12 Octadecadienoic Acid
  • Acid, 9,12-Octadecadienoic
  • 9-trans,12-trans-Octadecadienoic Acid
  • Linoelaidic Acid
  • Linoelaidic Acid, (E,Z)-Isomer
  • Linoleate
  • Linoleic Acid, (E,E)-Isomer
  • Linoleic Acid, (Z,E)-Isomer
  • Linoleic Acid, (Z,Z)-Isomer
  • Linoleic Acid, (Z,Z)-Isomer, 14C-Labeled
  • Linoleic Acid, Ammonium Salt, (Z,Z)-Isomer
  • Linoleic Acid, Calcium Salt, (Z,Z)-Isomer
  • Linoleic Acid, Potassium Salt, (Z,Z)-Isomer
  • Linoleic Acid, Sodium Salt, (E,E)-Isomer
  • Linoleic Acid, Sodium Salt, (Z,Z)-Isomer
  • Linolelaidic Acid
  • cis,cis-9,12-Octadecadienoic Acid
  • trans,trans-9,12-Octadecadienoic Acid
  • 9 trans,12 trans Octadecadienoic Acid

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

LINOLEIC ACIDS and LINOLEIC ACIDS, CONJUGATED are also available

MeSH Record

History Note

98; use LINOLEIC ACID (NM) 1981-97

MeSH Record

Previous Indexing

  • Fatty Acids, Unsaturated (1981-1983)
  • Linoleic Acids (1981-1997)

MeSH Hierarchy

Tree Numbers

  1. D10w.251w.355w.310w.515.500w
  2. D10w.251w.355w.343w.500.500w

AMA Style

References

  1. National Library of Medicine. Linoleic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D019787. http://id.nlm.nih.gov/mesh/2026/D019787
  2. Linoleic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Linoleic_acid
  3. Linoleic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q407426
  4. Linoleic Acid. In: PubChem Compound. CID 5280450. https://pubchem.ncbi.nlm.nih.gov/compound/5280450