Chemicals and Drugs

Lipid Peroxides

Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin E, structural separation or low oxygen tension.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin E, structural separation or low oxygen tension.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

13 entry terms
  • Fatty Acid Hydroperoxide
  • Fatty Acid Hydroperoxides
  • Lipid Hydroperoxide
  • Lipid Peroxide
  • Lipoperoxide
  • Lipoperoxides
  • Acid Hydroperoxide, Fatty
  • Acid Hydroperoxides, Fatty
  • Hydroperoxide, Fatty Acid
  • Hydroperoxide, Lipid
  • Hydroperoxides, Fatty Acid
  • Peroxide, Lipid
  • Peroxides, Lipid

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

80

MeSH Record

Previous Indexing

  • Lipids (1966-1979)
  • Peroxides (1966-1979)

MeSH Hierarchy

Tree Numbers

  1. D01w.248w.497w.158w.685w.750w.637
  2. D01w.339w.431w.374w.637
  3. D01w.650w.550w.750w.600
  4. D02w.389w.593w.374w.637
  5. D10w.440

MeSH Record

NLM Classification

QU 85

AMA Style

References

  1. National Library of Medicine. Lipid Peroxides. Medical Subject Headings (MeSH). 2026. Unique ID D008054. http://id.nlm.nih.gov/mesh/2026/D008054
  2. Lipid Peroxides. In: Wikidata. https://www.wikidata.org/wiki/Q76617139