Chemicals and Drugs

Lipoprotein Lipase

An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.

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Classification

Broader headings

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See Also

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Synonyms

19 entry terms
  • Diacylglycerol Lipase
  • Diglyceride Lipase
  • Heparin-Clearing Factor
  • Lipemia-Clearing Factor
  • Post-Heparin Lipase
  • Postheparin Lipase
  • Postheparin Lipoprotein Lipase
  • Factor, Heparin-Clearing
  • Factor, Lipemia-Clearing
  • Heparin Clearing Factor
  • Lipase, Diacylglycerol
  • Lipase, Diglyceride
  • Lipase, Lipoprotein
  • Lipase, Post-Heparin
  • Lipase, Postheparin
  • Lipase, Postheparin Lipoprotein
  • Lipemia Clearing Factor
  • Lipoprotein Lipase, Postheparin
  • Post Heparin Lipase

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Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/defic: consider also HYPERLIPOPROTEINEMIA TYPE I

MeSH Record

History Note

HEPARIN-CLEARING FACTOR & LIPEMIA-CLEARING FACTOR were see under LIPOPROTEIN LIPASE 1963-80

MeSH Hierarchy

Tree Number

  1. D08.811w.277w.352w.100.430

MeSH Record

NLM Classification

QU 136

AMA Style

References

  1. National Library of Medicine. Lipoprotein Lipase. Medical Subject Headings (MeSH). 2026. Unique ID D008071. http://id.nlm.nih.gov/mesh/2026/D008071
  2. Lipoprotein Lipase. In: Wikidata. https://www.wikidata.org/wiki/Q24774730