Chemicals and Drugs

Lisuride

An ergot derivative that acts as an agonist at dopamine D2 receptors (DOPAMINE AGONISTS). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (SEROTONIN RECEPTOR AGONISTS).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An ergot derivative that acts as an agonist at dopamine D2 receptors (DOPAMINE AGONISTS). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (SEROTONIN RECEPTOR AGONISTS).

Chemical Identity

Chemical Information

Molecular Formula
C20H26N4O
Molecular Weight
338.4 g/mol
CAS Registry No.
18016-80-3
IUPAC Name
3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea
InChIKey
BKRGVLQUQGGVSM-KBXCAEBGSA-N
SMILES
CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C
MeSH Unique ID
D008090
Source
PubChem CID 28864

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

21 entry terms
  • Lysurid
  • Methylergol Carbamide
  • Carbamide, Methylergol
  • Arolac
  • Cuvalit
  • Dopergin
  • Dopergine
  • Lisuride Hydrochloride
  • Lisuride Maleate
  • Lisuride Maleate (1:1)
  • Lisuride Maleate, (8beta)-Isomer
  • Lisuride Mesylate
  • Lisuride Phosphate (1:1)
  • Lisuride, (8alpha)-(+-)-Isomer
  • Lysenyl
  • Lysuride Hydrogen Maleate
  • Revanil
  • Hydrochloride, Lisuride
  • Hydrogen Maleate, Lysuride
  • Maleate, Lisuride
  • Mesylate, Lisuride

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under ERGOLINES 1979-90

MeSH Record

Previous Indexing

  • Ergolines (1969-1978)
  • Ergot Alkaloids (1966-1968)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.327.287.417w
  2. D03w.633.400.439.560w

MeSH Record

NLM Classification

QV 174

AMA Style

References

  1. National Library of Medicine. Lisuride. Medical Subject Headings (MeSH). 2026. Unique ID D008090. http://id.nlm.nih.gov/mesh/2026/D008090
  2. Lisuride. In: Wikipedia. https://en.wikipedia.org/wiki/Lisuride
  3. Lisuride. In: Wikidata. https://www.wikidata.org/wiki/Q424446
  4. Lisuride. In: PubChem Compound. CID 28864. https://pubchem.ncbi.nlm.nih.gov/compound/28864