Chemicals and Drugs

Lorazepam

A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Chemical Identity

Chemical Information

Molecular Formula
C15H10Cl2N2O2
Molecular Weight
321.2 g/mol
CAS Registry No.
846-49-1
IUPAC Name
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
InChIKey
DIWRORZWFLOCLC-UHFFFAOYSA-N
SMILES
C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl
MeSH Unique ID
D008140
Source
PubChem CID 3958

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

31 entry terms
  • Apo-Lorazepam
  • Ativan
  • Donix
  • Duralozam
  • Durazolam
  • Idalprem
  • Laubeel
  • Lorazep Von Ct
  • Lorazepam Medical
  • Lorazepam-Neuraxpharm
  • Lorazepam-Ratiopharm
  • Novo-Lorazem
  • Nu-Loraz
  • Orfidal Wyeth
  • Sedicepan
  • Sinestron
  • Somagerol
  • Temesta
  • Tolid
  • Témesta
  • WY-4036
  • Apo Lorazepam
  • Lorazepam Neuraxpharm
  • Lorazepam Ratiopharm
  • Medical, Lorazepam
  • Novo Lorazem
  • Nu Loraz
  • Von Ct, Lorazep
  • WY 4036
  • WY4036
  • Wyeth, Orfidal

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

84(75); was see under BENZODIAZEPINE TRANQUILIZERS 1975-83

MeSH Record

Previous Indexing

  • Benzodiazepinones (1974)
  • Chlorobenzenes (1974)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.079.080w.070.450w

AMA Style

References

  1. National Library of Medicine. Lorazepam. Medical Subject Headings (MeSH). 2026. Unique ID D008140. http://id.nlm.nih.gov/mesh/2026/D008140
  2. Lorazepam. In: Wikipedia. https://en.wikipedia.org/wiki/Lorazepam
  3. Lorazepam. In: Wikidata. https://www.wikidata.org/wiki/Q408265
  4. Lorazepam. In: PubChem Compound. CID 3958. https://pubchem.ncbi.nlm.nih.gov/compound/3958