Chemicals and Drugs

Low-Molecular-Weight Heparin

Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.

MeSH Record

Classification

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Heparin, Low-Molecular-Weight
  • LMWH
  • Low Molecular Weight Heparin
  • Heparin, Low Molecular Weight

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/antag = probably HEPARIN ANTAGONISTS

MeSH Record

History Note

94; was ENOXAPARIN 1992-93, was HEPARIN, LOW MOLECULAR WEIGHT 1988-91; HEPARIN, LOW MOLECULAR WEIGHT was see ENOXAPARIN 1992-93; LOW-MOLECULAR-WEIGHT HEPARIN was LOW MOLECULAR WEIGHT HEPARIN 1988-93

MeSH Record

Previous Indexing

  • Heparin (1966-1987)

MeSH Hierarchy

Tree Number

  1. D09w.698w.373w.400w.300w

MeSH Record

NLM Classification

QV 193

AMA Style

References

  1. National Library of Medicine. Low-Molecular-Weight Heparin. Medical Subject Headings (MeSH). 2026. Unique ID D006495. http://id.nlm.nih.gov/mesh/2026/D006495
  2. Low-Molecular-Weight Heparin. In: Wikipedia. https://en.wikipedia.org/wiki/Low-molecular-weight_heparin
  3. Low-Molecular-Weight Heparin. In: Wikidata. https://www.wikidata.org/wiki/Q2750727