Chemicals and Drugs

Lumefantrine

A fluorene derivative that is used in combination with ARTEMETHER for the treatment of MALARIA (see ARTEMETHER-LUMEFANTRINE DRUG COMBINATION).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fluorene derivative that is used in combination with ARTEMETHER for the treatment of MALARIA (see ARTEMETHER-LUMEFANTRINE DRUG COMBINATION).

Chemical Identity

Chemical Information

Molecular Formula
C30H32Cl3NO
Molecular Weight
528.9 g/mol
CAS Registry No.
82186-77-4
IUPAC Name
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol
InChIKey
DYLGFOYVTXJFJP-MYYYXRDXSA-N
SMILES
CCCCN(CCCC)CC(C1=CC(=CC\2=C1C3=C(/C2=C/C4=CC=C(C=C4)Cl)C=C(C=C3)Cl)Cl)O
MeSH Unique ID
D000078102
Source
PubChem CID 6437380

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • 9H-Fluorene-4-methanol, 2,7-dichloro-9-((4-chlorophenyl)methylene)-alpha-((dibutylamino)methyl)-, (Z)-
  • Benflumetol
  • Benflumetol, (+)-isomer
  • Benflumetol, (+-)-isomer
  • Benflumetol, (-)-isomer

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1996)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.389.650w
  2. D04w.615w.389.650w

AMA Style

References

  1. National Library of Medicine. Lumefantrine. Medical Subject Headings (MeSH). 2026. Unique ID D000078102. http://id.nlm.nih.gov/mesh/2026/D000078102
  2. Lumefantrine. In: Wikipedia. https://en.wikipedia.org/wiki/Lumefantrine
  3. Lumefantrine. In: Wikidata. https://www.wikidata.org/wiki/Q904464
  4. Lumefantrine. In: PubChem Compound. CID 6437380. https://pubchem.ncbi.nlm.nih.gov/compound/6437380