Chemicals and Drugs

Lurasidone Hydrochloride

A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER.

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Lurasidone HCl
  • HCl, Lurasidone
  • Hydrochloride, Lurasidone
  • Latuda
  • Lurasidone
  • N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide
  • SM 13496
  • SM-13,496
  • SM-13496
  • SM13496
  • 13496, SM
  • SM 13,496
  • SM13,496

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (2008)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Lurasidone Hydrochloride. Medical Subject Headings (MeSH). 2026. Unique ID D000069056. http://id.nlm.nih.gov/mesh/2026/D000069056
  2. Lurasidone Hydrochloride. In: Wikidata. https://www.wikidata.org/wiki/Q27882070