Chemicals and Drugs

MSH Release-Inhibiting Hormone

A hypothalamic tripeptide, enzymatic degradation product of OXYTOCIN, that inhibits the release of MELANOCYTE-STIMULATING HORMONES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A hypothalamic tripeptide, enzymatic degradation product of OXYTOCIN, that inhibits the release of MELANOCYTE-STIMULATING HORMONES.

Chemical Identity

Chemical Information

Molecular Formula
C13H24N4O3
Molecular Weight
284.35 g/mol
CAS Registry No.
9083-38-9
IUPAC Name
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
InChIKey
NOOJLZTTWSNHOX-UWVGGRQHSA-N
SMILES
CC(C)C[C@@H](C(=O)NCC(=O)N)NC(=O)[C@@H]1CCCN1
MeSH Unique ID
D009075
Source
PubChem CID 92910

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • H-Pro-Leu-Gly-NH2
  • MIF-1
  • MIF-I
  • MSH Release-Inhibiting Factor
  • Melanocyte-Stimulating Hormone Release-Inhibiting Factor
  • Melanocyte-Stimulating Hormone Release-Inhibiting Hormone
  • Melanostatin
  • Oxytocin (7-9)
  • Pro-Leu-Gly-NH2
  • Pro-Leu-Glyamide
  • Prol-Leu-Gly-NH2
  • Prolyl-Leucyl-Glycinamide
  • Prolylleucylglycinamide
  • Prol Leu Gly NH2
  • Prolyl Leucyl Glycinamide

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

75

MeSH Record

Previous Indexing

  • Hypothalamo-Hypophyseal System (1966-1974)
  • Hypothalamus (1966-1974)
  • MSH (1966-1974)
  • Oligopeptides (1973-1974)
  • Peptides (1971-1973)
  • Pituitary Hormone-Releasing Hormones (1971-1974)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.327.700.500w
  2. D12.644w.400w.400.700.500w
  3. D12.644w.548w.365.700.500w
  4. D12.776w.631w.650w.405.700.500w

AMA Style

References

  1. National Library of Medicine. MSH Release-Inhibiting Hormone. Medical Subject Headings (MeSH). 2026. Unique ID D009075. http://id.nlm.nih.gov/mesh/2026/D009075
  2. MSH Release-Inhibiting Hormone. In: Wikipedia. https://en.wikipedia.org/wiki/Melanocyte-inhibiting_factor
  3. MSH Release-Inhibiting Hormone. In: Wikidata. https://www.wikidata.org/wiki/Q6811443
  4. MSH Release-Inhibiting Hormone. In: PubChem Compound. CID 92910. https://pubchem.ncbi.nlm.nih.gov/compound/92910