Diseases

Malformations of Cortical Development

Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.

MeSH Record

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MeSH Record

Synonyms

15 entry terms
  • Malformations of Cerebral Cortex Development
  • Cortical Development Malformation
  • Cortical Development Malformations
  • Development Malformation, Cortical
  • Cerebral Cortical Dysplasia
  • Cortical Dysplasia
  • Cortical Dysplasia, Cerebral
  • Generalized Cortical Dysplasia
  • Cerebral Cortical Dysplasias
  • Cortical Dysplasia, Generalized
  • Cortical Dysplasias
  • Dysplasia, Cerebral Cortical
  • Dysplasia, Cortical
  • Dysplasia, Generalized Cortical
  • Generalized Cortical Dysplasias

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2008

MeSH Record

Previous Indexing

  • Cerebral Cortex/abnormalities (1995-2007)

MeSH Hierarchy

Tree Numbers

  1. C10w.500w.507
  2. C16w.131w.666w.507

AMA Style

References

  1. National Library of Medicine. Malformations of Cortical Development. Medical Subject Headings (MeSH). 2026. Unique ID D054220. http://id.nlm.nih.gov/mesh/2026/D054220
  2. Malformations of Cortical Development. In: Wikidata. https://www.wikidata.org/wiki/Q2852248