Diseases

Mantle-Cell Lymphoma

A form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the CYCLIN D1 gene (GENES, BCL-1).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the CYCLIN D1 gene (GENES, BCL-1).

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

25 entry terms
  • Diffuse Lymphocytic Lymphoma, Poorly-Differentiated
  • Lymphocytic Lymphoma, Diffuse, Poorly Differentiated
  • Lymphocytic Lymphoma, Diffuse, Poorly-Differentiated
  • Lymphoma, Centrocytic Small-Cell
  • Lymphoma, Lymphocytic, Diffuse, Intermediate Differentiated
  • Lymphoma, Lymphocytic, Diffuse, Poorly-Differentiated
  • Lymphoma, Mantle-Cell
  • Lymphoma, Small-Cell, Centrocytic
  • Mantle-Zone Lymphoma
  • Centrocytic Small-Cell Lymphoma
  • Centrocytic Small-Cell Lymphomas
  • Diffuse Lymphocytic Lymphoma, Poorly Differentiated
  • Lymphoma, Centrocytic Small Cell
  • Lymphoma, Mantle Cell
  • Lymphoma, Mantle-Zone
  • Lymphomas, Centrocytic Small-Cell
  • Lymphomas, Mantle-Cell
  • Lymphomas, Mantle-Zone
  • Mantle Cell Lymphoma
  • Mantle Zone Lymphoma
  • Mantle-Cell Lymphomas
  • Mantle-Zone Lymphomas
  • Small-Cell Lymphoma, Centrocytic
  • Small-Cell Lymphomas, Centrocytic
  • Lymphoma, Lymphocytic, Intermediate

MeSH Record

Aspects Covered

37 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

History Note

2000; for LYMPHOMA, LYMPHOCYTIC, DIFFUSE, INTERMEDIATE; LYMPHOCYTIC LYMPHOMA, DIFFUSE, POORLY-DIFFERENTIATED; LYMPHOMA, CENTROCYTIC SMALL-CELL; LYMPHOMA, LYMPHOCYTIC, DIFFUSE, POORLY-DIFFERENTIATED; & LYMPHOMA, SMALL-CELL, CENTROCYTIC use LYMPHOMA, SMALL CLEAVED-CELL, DIFFUSE 1991-1999

MeSH Record

Previous Indexing

  • Lymphoma, B-Cell (1992-1999)
  • Lymphoma, Non-Hodgkin (1992-1999)

MeSH Hierarchy

Tree Numbers

  1. C04w.557.386w.480w.525w
  2. C15.604w.515w.569w.480w.525w
  3. C20w.683w.515w.761w.480w.525w

AMA Style

References

  1. National Library of Medicine. Mantle-Cell Lymphoma. Medical Subject Headings (MeSH). 2026. Unique ID D020522. http://id.nlm.nih.gov/mesh/2026/D020522
  2. Mantle-Cell Lymphoma. In: Wikipedia. https://en.wikipedia.org/wiki/Mantle_cell_lymphoma
  3. Mantle-Cell Lymphoma. In: Wikidata. https://www.wikidata.org/wiki/Q268713