Phenomena and Processes

Matrix Attachment Regions

Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

30 entry terms
  • MAR Elements
  • Matrix-Attached Regions
  • SAR Elements
  • Scaffold Attachment Regions
  • Scaffold-Attached Regions
  • Element, MAR
  • Element, SAR
  • Elements, MAR
  • Elements, SAR
  • MAR Element
  • Matrix Attached Regions
  • Matrix Attachment Region
  • Matrix-Attached Region
  • Region, Matrix Attachment
  • Region, Matrix-Attached
  • Region, Scaffold Attachment
  • Region, Scaffold-Attached
  • Regions, Matrix Attachment
  • Regions, Matrix-Attached
  • Regions, Scaffold Attachment
  • Regions, Scaffold-Attached
  • SAR Element
  • Scaffold Attached Regions
  • Scaffold Attachment Region
  • Scaffold-Attached Region
  • MAR-SAR Recognition Signature Sequence
  • MRS Sequence
  • MAR SAR Recognition Signature Sequence
  • MRS Sequences
  • Sequences, MRS

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, physiology, radiation effects.

MeSH Record

History Note

2004

MeSH Record

Previous Indexing

  • Nuclear Matrix/metabolism (1990-2003)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Matrix Attachment Regions. Medical Subject Headings (MeSH). 2026. Unique ID D045170. http://id.nlm.nih.gov/mesh/2026/D045170
  2. Matrix Attachment Regions. In: Wikipedia. https://en.wikipedia.org/wiki/Scaffold/matrix_attachment_region
  3. Matrix Attachment Regions. In: Wikidata. https://www.wikidata.org/wiki/Q3931949