Chemicals and Drugs

Mazindol

Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.

Chemical Identity

Chemical Information

Molecular Formula
C16H13ClN2O
Molecular Weight
284.74 g/mol
CAS Registry No.
22232-71-9
IUPAC Name
5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol
InChIKey
ZPXSCAKFGYXMGA-UHFFFAOYSA-N
SMILES
C1CN2C(=N1)C3=CC=CC=C3C2(C4=CC=C(C=C4)Cl)O
MeSH Unique ID
D008454
Source
PubChem CID 4020

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Mazindole
  • AN-448
  • Diestet
  • Mazanor
  • Sanjorex
  • Sanorex
  • Solucaps
  • Teronac
  • Teronak
  • AN448

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under INDOLES 1975-90

MeSH Record

Previous Indexing

  • Imidazoles (1972-1974)
  • Indoles (1972-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Mazindol. Medical Subject Headings (MeSH). 2026. Unique ID D008454. http://id.nlm.nih.gov/mesh/2026/D008454
  2. Mazindol. In: Wikipedia. https://en.wikipedia.org/wiki/Mazindol
  3. Mazindol. In: Wikidata. https://www.wikidata.org/wiki/Q255680
  4. Mazindol. In: PubChem Compound. CID 4020. https://pubchem.ncbi.nlm.nih.gov/compound/4020