Structured Summary
Abstract
A benzene-sulfonamide-furan. It is used as a diuretic that affects the concentrating ability of the KIDNEY, increases SODIUM CHLORIDE excretion, but may not spare POTASSIUM. It inhibits CARBONIC ANHYDRASES and may increase the blood URIC ACID level.
Chemical Identity
Chemical Information
- Molecular Formula
- C13H19ClN2O5S2
- Molecular Weight
- 382.9 g/mol
- CAS Registry No.
- 7195-27-9
- IUPAC Name
- 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide
- InChIKey
- SMNOERSLNYGGOU-UHFFFAOYSA-N
- SMILES
- CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
- MeSH Unique ID
- D008529
- Source
- PubChem CID 4047
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(76); was see under DIURETICS, SULFAMYL 1976-90
MeSH Record
Previous Indexing
- Diuretics, Sulfamyl (1974-1975)
- Furans (1972-1975)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Mefruside. Medical Subject Headings (MeSH). 2026. Unique ID D008529. http://id.nlm.nih.gov/mesh/2026/D008529
- Mefruside. In: Wikipedia. https://en.wikipedia.org/wiki/Mefruside
- Mefruside. In: Wikidata. https://www.wikidata.org/wiki/Q6807947
- Mefruside. In: PubChem Compound. CID 4047. https://pubchem.ncbi.nlm.nih.gov/compound/4047