Chemicals and Drugs

Mepivacaine

A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)

Chemical Identity

Chemical Information

Molecular Formula
C15H22N2O
Molecular Weight
246.35 g/mol
CAS Registry No.
96-88-8
IUPAC Name
N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
InChIKey
INWLQCZOYSRPNW-UHFFFAOYSA-N
SMILES
CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C
MeSH Unique ID
D008619
Source
PubChem CID 4062

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

18 entry terms
  • Carbocaine
  • Carbocaïne
  • Isocaine
  • Isogaine
  • Meaverin
  • Mecain
  • Mepihexal
  • Mepivacain-Injektopas
  • Mepivacaina Braun
  • Mepivacaine Hydrochloride
  • Mepivacaine Monohydrochloride
  • Mepivastesin
  • Polocaine
  • Scandicain
  • Scandicaine
  • Scandinibsa
  • Scandonest
  • Mepivacain Injektopas

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D03w.383.621.450w

AMA Style

References

  1. National Library of Medicine. Mepivacaine. Medical Subject Headings (MeSH). 2026. Unique ID D008619. http://id.nlm.nih.gov/mesh/2026/D008619
  2. Mepivacaine. In: Wikipedia. https://en.wikipedia.org/wiki/Mepivacaine
  3. Mepivacaine. In: Wikidata. https://www.wikidata.org/wiki/Q416760
  4. Mepivacaine. In: PubChem Compound. CID 4062. https://pubchem.ncbi.nlm.nih.gov/compound/4062