Chemicals and Drugs

Metallothionein

A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • Isometallothionein
  • Metallothionein A
  • Metallothionein B
  • Metallothionein I
  • Metallothionein II
  • Metallothionein IIA

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Record

History Note

84(75); was see under METALLOPROTEINS 1975-83

MeSH Record

Previous Indexing

  • Metalloproteins (1973-1974)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QU 55.8

AMA Style

References

  1. National Library of Medicine. Metallothionein. Medical Subject Headings (MeSH). 2026. Unique ID D008668. http://id.nlm.nih.gov/mesh/2026/D008668
  2. Metallothionein. In: Wikipedia. https://en.wikipedia.org/wiki/Metallothionein
  3. Metallothionein. In: Wikidata. https://www.wikidata.org/wiki/Q416896