Chemicals and Drugs

Methaqualone

A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)

Chemical Identity

Chemical Information

Molecular Formula
C16H14N2O
Molecular Weight
250.29 g/mol
CAS Registry No.
72-44-6
IUPAC Name
2-methyl-3-(2-methylphenyl)quinazolin-4-one
InChIKey
JEYCTXHKTXCGPB-UHFFFAOYSA-N
SMILES
CC1=CC=CC=C1N2C(=NC3=CC=CC=C3C2=O)C
MeSH Unique ID
D008702
Source
PubChem CID 6292

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Metolquizolone
  • Ortonal
  • Methaqualone Hydrochloride
  • Optimil
  • Quaalude
  • Hydrochloride, Methaqualone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

68

MeSH Record

Previous Indexing

  • Hypnotics and Sedatives (1966-1967)
  • Tranquilizing Agents (1966-1967)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 85

AMA Style

References

  1. National Library of Medicine. Methaqualone. Medical Subject Headings (MeSH). 2026. Unique ID D008702. http://id.nlm.nih.gov/mesh/2026/D008702
  2. Methaqualone. In: Wikipedia. https://en.wikipedia.org/wiki/Methaqualone
  3. Methaqualone. In: Wikidata. https://www.wikidata.org/wiki/Q423912
  4. Methaqualone. In: PubChem Compound. CID 6292. https://pubchem.ncbi.nlm.nih.gov/compound/6292