Chemicals and Drugs

Methenamine

An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)

Chemical Identity

Chemical Information

Molecular Formula
C6H12N4
Molecular Weight
140.19 g/mol
CAS Registry No.
100-97-0
IUPAC Name
1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane
InChIKey
VKYKSIONXSXAKP-UHFFFAOYSA-N
SMILES
C1N2CN3CN1CN(C2)C3
MeSH Unique ID
D008709
Source
PubChem CID 4101

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Hexamethylenetetramine
  • Hexamine
  • Aminoform
  • Hexamine Silver
  • Methenamine Silver
  • Silver Methenamine
  • Urotropin
  • Methenamine, Silver
  • Silver, Hexamine
  • Silver, Methenamine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QV 243

AMA Style

References

  1. National Library of Medicine. Methenamine. Medical Subject Headings (MeSH). 2026. Unique ID D008709. http://id.nlm.nih.gov/mesh/2026/D008709
  2. Methenamine. In: Wikipedia. https://en.wikipedia.org/wiki/Hexamethylenetetramine
  3. Methenamine. In: Wikidata. https://www.wikidata.org/wiki/Q71969
  4. Methenamine. In: PubChem Compound. CID 4101. https://pubchem.ncbi.nlm.nih.gov/compound/4101