Chemicals and Drugs

Methicillin

One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.

Chemical Identity

Chemical Information

Molecular Formula
C17H20N2O6S
Molecular Weight
380.4 g/mol
CAS Registry No.
61-32-5
IUPAC Name
(2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChIKey
RJQXTJLFIWVMTO-TYNCELHUSA-N
SMILES
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)O)C
MeSH Unique ID
D008712
Source
PubChem CID 6087

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

8 entry terms
  • Meticillin
  • Penicillin, Dimethoxyphenyl
  • Dimethoxyphenyl Penicillin
  • Methicillin Hydrate, Monosodium Salt
  • Methicillin Monohydrate, Monosodium Salt
  • Methicillin Sodium
  • Metin
  • Staphcillin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Methicillin. Medical Subject Headings (MeSH). 2026. Unique ID D008712. http://id.nlm.nih.gov/mesh/2026/D008712
  2. Methicillin. In: Wikipedia. https://en.wikipedia.org/wiki/Methicillin
  3. Methicillin. In: Wikidata. https://www.wikidata.org/wiki/Q409262
  4. Methicillin. In: PubChem Compound. CID 6087. https://pubchem.ncbi.nlm.nih.gov/compound/6087