Chemicals and Drugs

Methiothepin

A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.

Chemical Identity

Chemical Information

Molecular Formula
C20H24N2S2
Molecular Weight
356.6 g/mol
CAS Registry No.
20229-30-5
IUPAC Name
1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine
InChIKey
RLJFTICUTYVZDG-UHFFFAOYSA-N
SMILES
CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)SC
MeSH Unique ID
D008719
Source
PubChem CID 4106

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Methiothepine
  • Metitepine
  • Methiothepin Maleate
  • Maleate, Methiothepin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(76); was see under DIBENZOTHIEPINS 1976-90

MeSH Record

Previous Indexing

  • Dibenzothiepins (1968-1975)
  • Piperazines (1973-1975)
  • Sulfides (1973-1975)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Methiothepin. Medical Subject Headings (MeSH). 2026. Unique ID D008719. http://id.nlm.nih.gov/mesh/2026/D008719
  2. Methiothepin. In: Wikipedia. https://en.wikipedia.org/wiki/Metitepine
  3. Methiothepin. In: Wikidata. https://www.wikidata.org/wiki/Q6824154
  4. Methiothepin. In: PubChem Compound. CID 4106. https://pubchem.ncbi.nlm.nih.gov/compound/4106